Yang Lab

Publications

(*marks co-first authorship; #marks co-corresponding authorship)

Yang Lab Publications

  • H Yang; Investigating heterogeneous cell-cycle progression using single-cell imaging approaches. Methods Mol Biol, In Press, 2024
  • M Zhang*, S Kim*, and H Yang; Non-canonical pathway for Rb inactivation and external signaling sequentially coordinate cell-cycle entry without CDK4/6 activity. Nat Comm, 14: 7847, 2023
  • E Lee*, S O’Keefe*, A Leong*, H Park, J Varadarajan, S Chowdhury, S Kim, A Shiva, R Friedman, H Remotti, A Fojo, H Yang, G Thurston, and M Kim; Angiopoietin-2 promotes hepatic metastatic growth by restricting T-cell infiltration to the liver in pancreatic neuroendocrine tumors. J. Clinical Investigation, 133(20):e167994, 2023
  • S Kim, J Armand, A Safonov, M Zhang, R Soni, G Schwartz, J McGuinness, H Hibshoosh, P Razavi, M Kim, S Chandarlapaty, and H Yang; Sequential activation of E2F via Rb degradation and c-Myc drives resistance to CDK4/6 inhibitors in breast cancer. Cell Rep, 42(11):113198, 2023
  • S Kim, R Carvajal, M Kim, and H Yang; Kinetics of RTK activation determine ERK reactivation and resistance to dual BRAF/MEK inhibition in melanoma. Cell Rep, 42(6):112570, 2023
  • H Park, A Shiva, P Cummings, S Kim, S Kim, A Leong, S Chowdhury, C Shawber, R Carvajal, G Thurston, J An, A Lund, H Yang, and M Kim; Angiopoietin-2-dependent peritumoral vascular destabilization promotes T-cell exclusion and limits immunotherapy in melanoma. Cancer Research, 15;83(12):1968-1983, 2023 (Cover Article)
  • S Kim, A Leong, M Kim#, and H Yang#; CDK4/6 initiates Rb inactivation and CDK2 activity coordinates cell-cycle commitment and G1/S transition. Sci Rep, 12: 16810, 2022
  • T Nguyen, E Shang, C Shu, S Kim, A Mela, N Humala, A Mahajan, H Yang, H Akman, C Quinzii, G Zhang, M Westhoff, G Karpel-Massler, J Bruce, P Canoll, and M Siegelin; Aurora kinase A inhibition reverses the warburg effect and elicits unique metabolic vulnerabilities in glioblastoma. Nat Comm, 12: 5203, 2021.
  • S Resnick, S Iketani, S Hong, A Zask, H Liu, S Kim, S Melore, M Nair, Y Huang, N Tay, R Rovis, H Yang, B Stockwell, D Ho, and A Chavez; A simplified cell-based assay to identify coronavirus 3CL protease inhibitors. J of Virology, 02374-20, 2021
  • R Meir, T Hirschhorn, S Kim, K Fallon, E Churchill, D Wu, H Yang, B Stockwell, and L Campos; Photon upconversion hydrogels for 3D optogenetics. Adv Func Materials, 2021

Hee Won’s Post Doc Publications

  • C Liu, Y Konagaya, M Chung, L Daigh, Y Fan, H Yang, K Terai, M Matsuda, and T Meyer; Altered G1 signaling order and commitment point in cells proliferating without CDK4/6 activity. Nat Comm, 11: 5305, 2020
  • H Yang*,#, S Cappell*, A Jaimovich*, C Liu, M Chung, S Regot, M Covert, and T Meyer#; Stress-mediated exit to quiescence restricted by progressively increasing persistence in CDK4/6 activation. eLife, 9, 2020
  • M Chung, C Liu, H Yang, M Koberlin, S Cappell, and T Meyer; Transient Hysteresis in CDK4/6 Activity Underlies Passage of the Restriction Point in G1. Mol Cell, 76(4): 562-573, 2019
  • T Tsai, S Collins, C Chan, P Lam, S Lou, H Yang, M Davidson, R Fischer, A Huttenlocher, T Meyer, J Ferrell, and J Theriot; Efficient Front-Rear Coupling in Neutrophil Chemotaxis by Dynamic Myosin II Localization. Dev Cell, 49(2): 189-205, 2019
  • H Yang#, M Chung, T Kudo, and T Meyer#; Competing memories of mitogen and p53 signaling control cell-cycle entry. Nature, 549: 404-408, 2017 (Cover article, Highlight in Nature, Faculty of 1000 recommended article)
  • A Hayer, L Shao, M Chung, L Joubert, H Yang, F Tsai, A Bisaria, E Betzig, and T Meyer; Polarized cadherin fingers guide collective endothelial cell migration. Nat Cell Biol, 18: 1311–1323, 2016 (Faculty of 1000 recommended article)
  • M Kim, B Allen, E Korhonen, M Nitschké, H Yang, P Baluk, P Saharinen, K Alitalo, C Daly, G Thurston, and D McDonald; Opposite actions of Angiopoietin-2 on Tie2 signaling and Foxo1 activation in the presence or absence of inflammation. J of Clinical Investigation, 126: 3511-3525, 2016
  • H Yang*,#, S Collins*,#, and T Meyer#; Locally excitable Cdc42 signals steer cells during chemotaxis. Nat Cell Biol, 18: 191-201, 2016 (Faculty of 1000 recommended article)
  • S Collins, H Yang, K Bonger, E Guignet, T Wandless, and T Meyer; Using light to shape chemical gradients for parallel and automated analysis of chemotaxis. Mol Sys Biol, 11(4): 804, 2015
  • F Tsai, A Seki, H Yang, A Hayer, S Carrasco, S Malmersjo, and T Meyer; A polarized Ca2+, diacylglycerol and STIM1 signalling system regulates directed cell migration. Nat Cell Biol, 16: 133-144. 2014 (Faculty of 1000 recommended article)

Hee Won’s PhD Publications

  • K Chang, D Woo, H Jung, S Lee, S Kim, J Won, T Kyung, H Park, N Kim, H Yang, J Park, E Hang, D Kim, and W Heo; Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling. Nat Comm, 5: 4057, 2014
  • H Yang, MK Shin, S Lee, J Kim, W Park, K Cho, T Meyer, and WD Heo; Cooperative activation of PI3K by Ras and Rho family small GTPases. Mol Cell, 47: 281-290, 2012 (Faculty of 1000 recommended article)
  • J Won*, H Yang*, S Shin*, J Lee, W Heo, and K Cho; The cross regulation between ERK and PI3K signaling patHays determines the tumoricidal efficacy of MEK inhibitor. J of Mol Cell Biol, 4: 153-163, 2012 (Cover article)
  • S Shin*, H Yang*, J Kim, W Heo, and K Cho; A hidden incoherent switch regulates RCAN1 in the calcineurin-NFAT signaling network. J of Cell Science, 124: 82-90, 2011 (Cover article)
  • K Lee, S Lee, WY Lee, H Yang, and W Heo; Visualizing dynamic interaction between calmodulin and calmodulin-related kinases via a monitoring method in live mammalian cells. Proc Natl Acad Sci, 107: 3412-3417, 2010
  • H Yang, H Lee, K Jang, C Park, H Yang, W Heo, and J Kim; Poly(amino acid)-coated iron oxide nanoparticles as ultra-small magnetic resonance probes. J of Materials Chemistry, 19: 4566-4574, 2009