Research Labs
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My research laboratory investigates the role of microtubule dynamics and tubulin post-translational modifications in neuronal physiology and at the onset of neurodegenerative and neuropathic disease.
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The Canman Lab investigates temporal and spatial regulation of cytokinesis.
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We mainly focus within the neurodegenerative disease space, but also engage in productive collaborations with outside fields, e.g. microbial biology, cancer biology and laboratory assisted evolution.
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We are interested in the mechanism that maintains genomic stability and metabolic homeostasis: how systemic signaling communicates with cell division process, how insulin initiates the insulin ...
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The Digital and Computational Pathology Laboratory (DCPL) performs acquisition of high resolution images of tissue slides, brightfield or fluorescence.
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The focus of our research is to understand the molecular mechanisms that drive immune and vascular changes in order to overcome the limitation of current anti-angiogenic therapy and immunotherapy.
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We aim to uncover the cellular and neural circuits mechanisms involved in spinal motor control, and how neuronal dysfunction leads to deficits observed in neurodegenerative diseases.
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The Precision Genomics Laboratory (PGL) is a new joint initiative designed to enhance patient care through genomic diagnostics, research, and education at CUMC.
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We study the development of proatherogenic metabolic abnormalities in insulin resistant individuals, and identify new therapeutic targets for improving these abnormalities.
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We focus on mechanisms of organelle and cytoskeletal quality control in health, aging and disease.
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The Vallee lab is interested in a variety of biological phenomena involving motor proteins, with a major emphasis on cytoplasmic dynein.
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Our laboratory studies how cells decide to proliferate in normal and cancer cells.