John P. Crapanzano, MD

Pathology - Anatomic & Clinical
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Dr. Crapanzano is an expert diagnostic pathologist with special expertise in cytopathology, including fine-needle aspiration biopsy. Dr. Crapanzano is available to perform and immediately interpret fine-needle aspiration biopsies of superficial palpable lesions and to evaluate cytologic material obtained from radiologically-guided fine-needle aspiration biopsies. Dr. Crapanzano is available to consult on all areas of diagnostic cytology, including aspiration and exfoliative cytopathology.

Dr. Crapanzano received his MD from Louisiana State University School of Medicine in New Orleans, LA, and completed residency training in anatomic and clinical pathology at Louisiana State University Medical Center/Charity Hospital in New Orleans. He subsequently completed three consecutive fellowships, including Surgical Pathology at Vanderbilt University Medical Center (Nashville, TN) and Oncologic Pathology and Cytopathology at Memorial Sloan Kettering Cancer Center (New York, NY).

Before coming to Columbia University Medical Center in 2009, Dr. Crapanzano was at Memorial Sloan Kettering Cancer Center, where he participated in the surgical pathology and cytology services, and subsequently at Weill Cornell Medical Center, where participated in the cytopathology service and served as director of the cytology fellowship. In addition to his clinical responsibilities, he has lectured to students of cytotechnology, pathology residents, and cytopathology fellows. He has co-authored book chapters and published a number of articles on tumor cytomorphology and other cytopathology-related topics.


Areas of Expertise / Conditions Treated

  • Surgical Pathology

Academic Appointments

  • Associate Professor of Pathology & Cell Biology at CUMC

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center


  • Male

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Credentials & Experience

Education & Training

  • BS, 1988 Louisiana State University
  • MD, 1992 Louisiana State University School of Medicine
  • Internship: Charity Hospital Medical Center of Louisiana
  • Internship: Louisiana State University Medical Center
  • Residency: Louisiana State University Medical Center
  • Residency: Charity Hospital Medical Center of Louisiana
  • Residency: 1997 Louisiana State University Health Sciences Center
  • Fellowship: Memorial Sloan-Kettering Cancer Center, NY
  • Fellowship: Vanderbilt University Medical Center

Committees, Societies, Councils

College of American Pathologists

American Society for Clinical Pathology

United States and Canadian Academy of Pathology

American Society of Cytopathology

Papanicolaou Society of Cytopathology

Board Certifications

  • Cytopathology
  • Pathology-Anatomic/Pathology-Clinical


Areas of interest include cytomorphology of neoplastic and non-neoplastic lesions as well as advancing the field of cytopathology in today's era of personalized medicine.

Selected Publications

  • Canterbury CR, Fernandes H, Crapanzano JP, Murty VV, Mansukhani MM, Shu CA, Szabolcs M, Saqi A. ALK Gene Rearrangements in Lung Adenocarcinomas: Concordance of Immunohistochemistry, Fluorescence In Situ Hybridization, RNA In Situ Hybridization, and RNA Next-Generation Sequencing Testing. JTO Clin Res Rep. 2021 Sep 25;2(10):100223.
  • Pagan CA, Shu CA, Crapanzano JP, Lagos GG, Stoopler MB, Rizvi NA, Heymann JJ, Sonett JR, Fernandes H, Saqi A. Synchronous Pulmonary Adenocarcinomas. Am J Clin Pathol. 2020 Jun 8;154(1):57-69.
  • Saqi A, Mukhopadhyay S, Butt Y, Doxtader E, Heyman JJ, Larsen BT, Moreira AL, Patel A, Reynolds JP, Sung S, Crapanzano JP. E-cigarette or vaping product use-associated lung injury: What is the role of cytologic assessment? Cancer Cytopathol. 2020 Jun;128(6):371-380. 
  • Sung S, Shirazi M, Shu CA, Crapanzano JP, Saqi A. Pulmonary small cell carcinoma: Review, common and uncommon differentials, genomics and management. Diagn Cytopathol. 2020 Aug;48(8):790-803.
  • Sung S, Heymann JJ, Crapanzano JP, Moreira AL, Shu C, Bulman WA, Saqi A. Lung cancer cytology and small biopsy specimens: diagnosis, predictive biomarker testing, acquisition, triage, and management. J Am Soc Cytopathol. 2020 Sep-Oct;9(5):332-345.