Sohn Precision Medicine Program at Columbia University
Sohn Foundation Testing in the Laboratory for Personalized Genomic Medicine is available as below. For more information regarding this testing, email firstname.lastname@example.org.
Cancer Whole Exome Sequencing with Transcriptome
Detects actionable constitutional changes predisposing to cancer; detects cancer specific missense, indel and copy number changes as well as chimeric RNAs and RNAs with altered expression levels using combination of exome and transcriptome sequencing.
|CPT Codes:||81415, 81416, 81479|
|Methodology:||Next Generation Sequencing of mRNA and DNA|
|Turnaround Time:||60 Days – Turnaround times < 60 days are available for rush cases based on clinical context and prior discussion with the laboratory.|
The lab cannot accept FFPE blocks or frozen tissue blocks.
|Associated documents:||Cancer Genes (Cosmic):
COSMIC genes reported on
WES regions not guaranteed greater than 10 fold
COSMIC gene exons not guaranteed greater than 30 fold
Recurrent COSMIC mutations not guaranteed to be covered greater than 30 fold
|Secondary Findings:||ACMG Secondary Findings List|
|Forms:||1. Sohn Oncology Requisition Form
2. Sohn Conference Eligibility Checklist
3. Cancer Whole Exome Informed Consent
4. Insurance Pre-Authorization Form
5. CWES Letter of Medical Necessity Template