Sohn Precision Medicine Program at Columbia University
Sohn Foundation Testing in the Laboratory for Personalized Genomic Medicine is available as below. For more information regarding this testing, email sohnpgmorders@columbia.edu.
Cancer Whole Exome Sequencing with Transcriptome
Purpose: |
Detects actionable constitutional changes predisposing to cancer; detects cancer specific missense, indel and copy number changes as well as chimeric RNAs and RNAs with altered expression levels using combination of exome and transcriptome sequencing. |
CPT Codes: | 81415, 81416, 81479 |
Methodology: | Next Generation Sequencing of mRNA and DNA |
Turnaround Time: | 60 Days – Turnaround times < 60 days are available for rush cases based on clinical context and prior discussion with the laboratory. |
Specimen: |
The lab cannot accept FFPE blocks or frozen tissue blocks. |
Associated documents: | Cancer Genes (Cosmic): COSMIC genes reported on Coverage Disclaimer: WES regions not guaranteed greater than 10 fold COSMIC gene exons not guaranteed greater than 30 fold Recurrent COSMIC mutations not guaranteed to be covered greater than 30 fold |
Secondary Findings: | ACMG Secondary Findings List |
Forms: | 1. Sohn Oncology Requisition Form 2. Sohn Conference Eligibility Checklist 3. Cancer Whole Exome Informed Consent 4. Insurance Pre-Authorization Form 5. CWES Letter of Medical Necessity Template |