Patrice F. Spitalnik, MD

  • Professor of Pathology & Cell Biology at CUMC
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Patrice F. Spitalnik, M.D. is a Professor of Pathology and Cell Biology at CUMC, Columbia University College of Physicians and Surgeons. She is the Associate Director of the MD-PhD Program and teaches general pathology and surgical pathology to second and third year medical students, as well as to MD-PhD students. She is the Section Director of the first year medical student histology course in the first year Molecular Mechanisms course. She is the Co-Director of the Mechanisms and Practice Course in the Major Clinical Year of the College of Physicians. She recently created a web-based, on-line, teaching source of microscopic histology and pathology slides for the medical and dental school histology and pathology courses. She helped design new classrooms to facilitate the education using this technology. She created and directs a course for MD-PhD students on "Responsible Conduct of Research" in addition to a clinical medicine program for MD-PhD students during the PhD portion of the program. She runs a clinical program for graduate students in the Howard Hughes Medical Institute (HHMI) Medicine into Graduate Program at Columbia. She is interested in medical education related to the interface between basic research and clinical medicine and the training of physician-scientists. She has been invited to speak on “Teaching to Large Groups” and is interested in effective teaching methods for learning. Finally, Dr. Spitalnik teaches science to middle and high school students in the Washington Heights neighborhood of New York City and thereby hopes to increase the diversity of medical students and physician-scientists, by recruiting and training middle school, high school, and undergraduate students.


Academic Appointments

  • Professor of Pathology & Cell Biology at CUMC

Administrative Titles

  • Associate Director, MD-PhD Program


  • Female

Credentials & Experience

Education & Training

  • MD, 1978 University of Chicago
  • Residency: 1979 University of Rochester
  • Fellowship: 1985 National Institute of Health
  • Fellowship: 1987 University of Pennsylvania Medical School

Honors & Awards

Student Fellowship, Hastings Institute of Society, Ethics and the Life Sciences, Hastings-on-Hudson, NY

Phi Beta Kappa

Young Investigator Award, Academy of Clinical Laboratory Physicians and Scientists

Commendation for Outstanding Teaching (Class of 1995), University of Pennsylvania School of Medicine

Commendation for Outstanding Teaching (Class of 1999), University of Pennsylvania School of Medicine
Peter C. Nowell Teaching Award, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine

Commendation for Outstanding Teaching (Class of 2000), University of Pennsylvania School of Medicine

Commendation for Outstanding Teaching (Class of 2001), University of Pennsylvania School of Medicine

Herbert W. Mapstone Excellence in Teaching Prize, awarded to the best teacher of the second year (Class of 2002), University of Rochester School of Medicine and Dentistry

Herbert W. Mapstone Excellence in Teaching Prize, awarded to the best teacher of the second year (Class of 2003), University of Rochester School of Medicine and Dentistry

Faculty Marshall, Graduation, May 26, 2002, selected by the graduating class to lead the faculty

Alpha Omega Alpha

Glenda Garvey Teaching Fellow, Columbia University

Outstanding Teacher Award Class of 2013


Selected Publications

Raciti PM, Francis RO, Spitalnik PF, Schwartz J, Jhang JS. Acquired hemoglobin variants and exposure to glucose-6-phosphate dehydrogenase deficient red blood cell units during exchange transfusion for sickle cell disease in a patient requiring antigen-matched blood. J Clin Apher. 2013 Aug;28(4):325-9. doi: 10.1002/jca.21255. Epub 2013 Mar 1.

Marolt D, Campos IM, Bhumiratana S, Koren A, Petridis P, Zhang G, Spitalnik PF, Grayson WL, Vunjak-Novakovic G. Engineering bone tissue from human embryonic stem cells. Proc. Natl. Acad. Sci USA, 29;109 (22):8705-9, 2012.

Koniaris LG, Kaufman D, Zimmers, T, Wang N, Spitalnik PF, Henson L, Miller-Graziano C, Sitzmann JV. Two Third-Year Medical Student-Level Laboratory Shock Exercises without Large Animals. Surgical Infections. 5:4 343-348, 2004.

Schwimmer J, Nadasdy TA, Spitalnik PF, Kaplan KL, Zand MS. De novo thrombotic microangiopathy in renal transplant recipients: a comparison of hemolytic uremic syndrome with localized renal thrombotic microangiopathy. Am J Kidney Dis. 2003 Feb;41(2):471-9. Review.

Spitalnik PF, Spitalnik SL. Human carbohydrate blood group systems. In Principles of Transfusion Medicine (Simon T, Dzik W, Snyder E, Stowell C, Strauss R, eds.). Third Edition. Williams & Wilkins, Baltimore, 2002, pp. 92-110.

Spitalnik PF, di Sant-Agnese PA. Pathology of Cancer. In Clinical Oncology (8th Edition; Philip Rubin, ed.) WB Saunders Co., Philadelphia, 2001, pp 47-61.

Kaczorowski JM, Halterman JS, Spitalnik PF, Mannick E, Fong CT, Seaman JM. Pathology Teach and Tell: Congenital Hepatic Fibrosis and Autosomal Dominant Polycystic Kidney Disease. Ped. Path. Molec. Med. 20: 245, 2001.

Pahlsson P, Spitalnik SL, Spitalnik PF, Fantini J, Rakotonirainy O, Ghardashkhani S, Lindberg J, Konradsson P, Larson G. Characterization of galactosyl glycerolipids in the HT29 human colon carcinoma cell line. Arch Biochem Biophys. 2001 Dec 15;396(2):187-98.

Spitalnik PF, Spitalnik SL. The P blood group system: biochemical, serological, and clinical aspects. Transfus Med Rev.1995 Apr;9(2):110-22. Review.