Mythily Ganapathi, PhD

Profile Headshot


Academic Appointments

  • Assistant Professor of Pathology & Cell Biology at CUMC

Administrative Titles

  • Assistant Director, Cytogenetics


  • Female

Credentials & Experience

Education & Training

  • 1998 B.Sc. Honors (Biochemistry), University of Delhi
  • 2000 M.Sc. (Biomedical Sciences), University of Delhi
  • PhD, 2006 CSIR-Institute of Genomics and Integrative Biology (New Delhi, India)
  • Fellowship: 2017 Columbia University Medical Center


Selected Publications

1. Expanding the clinical spectrum of hereditary fibrosing poikiloderma with tendon contractures,
myopathy and pulmonary fibrosis due to FAM111B mutations. Mercier S, Küry S, Salort-Campana E,
Magot A, Agbim U, Besnard T, Bodak N, Bou-Hanna C, Bréhéret F, Brunelle P, Caillon F, Chabrol B,
Cormier-Daire V, David A, Eymard B, Faivre L, Figarella-Branger D, Fleurence E, Ganapathi M,
Gherardi R, Goldenberg A, Hamel A, Igual J, Irvine AD, Israël-Biet D, Kannengiesser C, Laboisse C, Le
Caignec C, Mahé JY, Mallet S, MacGowan S, McAleer MA, McLean I, Méni C, Munnich A, Mussini JM,
Nagy PL, Odel J, O'Regan GM, Péréon Y, Perrier J, Piard J, Puzenat E, Sampson JB, Smith F, Soufir N,
Tanji K, Thauvin C, Ulane C,Watson RM, Khumalo NP, Mayosi BM, Barbarot S, Bézieau S. Orphanet J
Rare Dis. 2015 Oct 15;10:135. doi: 10.1186/s13023-015-0352-4. PubMed PMID: 26471370; PubMed
Central PMCID: PMC4608180.

2. FTO variant associated with malformation syndrome. Rohena L, Lawson M, Guzman E, Ganapathi M,
Cho MT, Haverfield E, Anyane-Yeboa K. Am J Med Genet A. 2016 Apr;170(4):1023-8. doi:
10.1002/ajmg.a.37515. Epub 2015 Dec 24. PubMed PMID:26697951.

3. Distinct role for the tail module of Mediator in regulating SAGA- dependent, TATA-containing
genes in yeast. Ansari SA, Ganapathi M, Benschop JJ, Holstege FCP, Wade JT and Morse RH. EMBO J.
Oct 4;31(1):44-57.

4. Extensive role of the general regulatory factors, Abf1 and Rap1, in determining genome-wide
chromatin structure in budding yeast. Ganapathi M, Palumbo MJ, Ansari SA, He Q, Tsui K, Nislow C,
Morse RH. Nucleic Acids Res. 2011 Mar;39(6):2032-44.

5. An analysis of histone modifications in relation to sex specific chromatin
organization in the mealybug Maconellicoccus hirsutus. Mathur V, Mendiratta G,
Ganapathi M, Kennady PK, Dwarkanath BS, Pande G and Brahmachari V. Cytogenetic and Genome
Research. 2010;129(4) : 323-

6. Functional Anatomy of Polycomb and Trithorax Chromatin Landscapes in Drosophila Embryos.
Schuettengruber B*, Ganapathi M*, Leblanc B, Portoso M, Jaschek R, Tolhuis B, Lohuizen MV, Tanay
A, and Cavalli G. PLoS Biol. 2009 Jan 13;7(1):e13.