Harris H. Wang, PhD

Dr. Harris Wang - Assistant Professor of Pathology and Cell Biology

Overview

Academic Appointments

  • Assistant Professor of Systems Biology (in Pathology and Cell Biology)

Harris Wang is as an Assistant Professor at Columbia University in the Department of Systems Biology. Dr. Wang received B.S. degrees in mathematics and physics from MIT and a Ph.D. in Biophysics from Harvard, where he pioneered the Multiplex Automated Genome Engineering (MAGE) platform for rapid and combinatorial genome editing. Dr. Wang’s current research focuses on applying synthetic biology methods to manipulate microbial communities and mammalian systems. Using advanced approaches in genome engineering, gene synthesis, and next-generation sequencing, he studies how genomes are shaped and maintained by the environment, and how they evolve over time. His research group is developing enabling technologies in systems and synthetic biology to engineer microbial systems and mammalian cells in ways that could address key challenges in health, energy and the environment. Dr. Wang is the recipient of numerous awards including the Presidential Early Career Awards for Scientists and Engineers, NIH Director’s Early Independence Award, NSF CAREER Award, Sloan Research Award, ONR Young Investigator Award, and was named in Forbes’ 30 Under 30 in Science in 2012.

Email: hw2429@cumc.columbia.edu

Languages

  • Chinese

Credentials & Experience

Education & Training

  • PhD, Biophysics, Harvard University
  • BS, Mathematics, Massachusetts Institute of Technology
  • BS, Physics, Massachusetts Institute of Technology

Honors & Awards

Presidential Early Career Award for Scientists and Engineers (PECASE)

ONR Director of Research Early Career Award

ONR Young Investigator Award

Sloan Research Fellowship

NSF CAREER Award

Forbes 30 under 30 in Science in 2012

NIH Director’s Early Independence Award

Collegiate Inventors Competition Grand Prize Winner, National Inventors Hall of Fame 

National Science Foundation Graduate Fellowship

National Defense Science and Engineering Graduate Fellowship

National Merit Scholar

Research

Research Interests

  • Understanding the key principles that drive the formation, maintenance, and evolution of genomes within and across microbial populations

Grants

MAPPING HOST-MICROBE AND INTER-MICROBIAL NETWORKS AT ULTRA-HIGH SPATIAL RESOLUTION (Private)

Jul 1 2017 - Jun 30 2022

MICRON-SCALE SPATIAL METAGENOMIC MAPPING OF MICROBIAL BIOGEOGRAPHY IN THE GASTROINTESTINAL TRACT (Federal Gov)

Jun 1 2017 - May 31 2022

NEXT-GENERATION MASSIVELY PARALLEL CELLULAR BIOSURVEILLANCE AND RECORDING DEVICES (Federal Gov)

Apr 1 2017 - Mar 31 2022

CENTERS FOR CANCER SYSTEMS THERAPEUTICS (CAST) (Federal Gov)

Aug 8 2016 - Jul 31 2021

NOVEL GENETIC ENGINEERING TOOLS FOR FUNCTIONA (Federal Gov)

Apr 1 2017 - Mar 31 2021

ENGINEERED LIVING MATERIALS (Federal Gov)

Apr 1 2017 - Mar 31 2021

SIMONS SOCIETY OF FELLOWS - CARLOTTA RONDA (Private)

Jul 1 2017 - Jun 30 2020

A SYSTEMS APPROACH TO STUDY HORIZONTAL ACQUISITION OF REGULATORY DNA (Federal Gov)

Jan 1 2015 - Dec 31 2019

MODULAR AUTOMATED MICROBIAL BIOBANKING AND ANALYSIS (MAMBA) SYSTEM TO ENHANCE DOD-RELEVANT MICROBIOM (Federal Gov)

Jun 1 2018 - May 31 2019

ENGINEERING PROTOTROPHY IN MAMMALIAN CELLS (Federal Gov)

May 1 2017 - Oct 31 2018

A FOUNDATIONAL SYNTHETIC BIOLOGY TOOLBOX FOR ENGINEERING HUMAN BUT MICROBIOTA TOWARDS ENHANCING WARFIGHTER CAPABILITES (Federal Gov)

Jul 1 2015 - Jun 30 2018

SLOAN RESEARCH FELLOWSHIP IN COMPUTATIONAL & EVOLUTIONARY MOLECULAR BIOLOGY (Private)

Sep 15 2015 - Sep 14 2017

FUNCTIONAL METAGENOMIC REPROGRAMMING OF THE HUMAN MICROBIOME THROUGH MOBILOME ENGINEERING (Federal Gov)

Mar 1 2013 - Aug 31 2017

IN SITU GENOME ENGINEERING OF UNCULTURABLE MICROBES AND GENOMIC RECORDING TO LIMIT THE ROBUSTNESS OF THE GENETIC CODE (Federal Gov)

Jul 1 2015 - Sep 30 2016

A MINIMALLY INVASIVE SYNTHETIC BIOLOGY-DRIVEN APPROACH FOR NATURAL PRODUCTS DISCOVERY (Federal Gov)

Jul 1 2015 - Apr 30 2016