Govind Bhagat, MBBS

Pathology - Anatomic & Clinical
Hematology
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Overview

Areas of Expertise / Conditions Treated

  • Acute Leukemia
  • Acute Lymphoblastic Leukemia
  • Acute Myelogenous Leukemia/AML
  • Anatomic Pathology
  • Bone Marrow Disorders
  • Bone Marrow Failure Diseases
  • Castleman Disease
  • Celiac Disease
  • Chronic Lymphocytic Leukemia
  • Chronic Myelogenous Leukemia
  • Clinical Research
  • Cutaneous Lymphoma
  • Cutaneous T-Cell Lymphoma
  • Essential Thrombocythemia
  • Follicular Lymphoma
  • Hematopathology
  • Hematopoiesis
  • HIV-Related Blood Disorders
  • Hodgkins Lymphoma
  • Immunocompromised Host Diseases
  • Immunohistochemistry
  • Laboratory Medicine
  • Leukemia
  • Lymphoma
  • Mantle Cell Lymphoma
  • Molecular Cancer Testing
  • Multiple Myeloma
  • Myelodysplastic Syndrome
  • Myeloproliferative Disorder
  • Non-Hodgkin's Lymphoma
  • Pediatric Leukemia
  • Polycythemia Vera
  • Second Opinions
  • Spleen Disease
  • T-Cell Lymphoma
  • Transplantation Pathology
  • Waldenstrom's Macroglobulinemia

Academic Appointments

  • Professor of Pathology and Cell Biology at CUMC

Administrative Titles

  • Director, Hematopathology Division

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center

Languages

  • Hindi

Gender

  • Male

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Credentials & Experience

Education & Training

  • Delhi University College of Medical Sciences
  • Internship: Guru Tegh Bahadur Hopital - India
  • Residency: Columbia Presbyterian Medical Center
  • Residency: Mount Sinai Medical Center
  • Residency: 2000 NewYork-Presbyterian/Columbia University Medical C
  • Fellowship: NewYork-Presbyterian Hospital
  • Fellowship: Armed Forces Institute

Committees, Societies, Councils

Societies/Memberships

  • United States and Canadian Academy of Pathology
  • Society for Hematopathology
  • American Society of Hematology
  • International Extranodal Lymphoma Study Group
  • International Primary Central Nervous System Lymphoma Collaborative Group
  • American Association for Cancer Research
  • Society for Immunotherapy of Cancer
  • Society for Mucosal Immunology
  • North American Society for the Study of Celiac Disease, founding member
  • International Society for the Study of Celiac Disease

Department and University Committees:

  • 2005-present: Faculty Council of the Faculty of Medicine
  • 2016-present: Academy of Clinical Excellence - Inaugural/Steering and Communications Committees

Board Certifications

  • Hematology
  • Anatomic Pathology and Clinical Pathology

Research

Research Interests

  • Immunopathogenesis of celiac disease
  • Leukemias and myeloid disorders
  • Pathogenesis and genetic characteristics of lymphomas

Selected Publications

  • Wang RC, Wei Y, An Z, Zou Z, Xiao G, Bhagat G, White M, Reichelt J, Levine B. Akt-Mediated Regulation of Autophagy and Tumorigenesis through Beclin 1 Phosphorylation. Science. 2012, 338(6109):956-959.
  • Margolskee E, Jobanputra V, Lewis SK, Alobeid B, Green PH, Bhagat G. Indolent Small Intestinal CD4+ T-cell Lymphoma Is a Distinct Entity with Unique Biologic and Clinical Features. PLoS One. 2013, 8(7):e68343.
  • DeGaetani M, Tennyson CA, Lebwohl B, Lewis SK, Abu Daya H, Arguelles-Grande C, Bhagat G, Green PH. Villous atrophy and negative celiac serology: a diagnostic and therapeutic dilemma. Am J Gastroenterol. 2013, 108(5):647-653.
  • Pasqualucci L, Khiabanian H, Fangazio M, Vasishtha M, Messina M, Holmes AB, Ouillette P, Trifonov V, Rossi D, Tabbò F, Ponzoni M, Chadburn A, Murty VV, Bhagat G, Gaidano G, Inghirami G, Malek SN, Rabadan R, Dalla-Favera R. Genetics of follicular lymphoma transformation. Cell Rep. 2014, 6(1):130-140.
  • Palomero T, Couronné L, Khiabanian H, Kim MY, Ambesi-Impiombato A, Perez-Garcia A, Carpenter Z, Abate F, Allegretta M, Haydu JE, Jiang X, Lossos IS, Nicolas C, Balbin M, Bastard C, Bhagat G, Piris MA, Campo E, Bernard OA, Rabadan R, Ferrando AA. Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas. Nat Genet. 2014, 46(2):166-170.
  • Kode A, Manavalan JS, Mosialou I, Bhagat G, Rathinam CV, Luo N, Khiabanian H, Lee A, Murty VV, Friedman R, Brum A, Park D, Galili N, Mukherjee S, Teruya-Feldstein J, Raza A, Rabadan R, Berman E, Kousteni S. Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts. Nature. 2014, 506(7487):240-244.
  • Miranda RN, Aladily TN, Prince HM, Kanagal-Shamanna R, de Jong D, Fayad LE, Amin MB, Haideri N, Bhagat G, Brooks GS, Shifrin DA, O'Malley DP, Cheah CY, Bacchi CE, Gualco G, Li S, Keech JA Jr, Hochberg EP, Carty MJ, Hanson SE, Mustafa E, Sanchez S, Manning JT Jr, Xu-Monette ZY, Miranda AR, Fox P, Bassett RL, Castillo JJ, Beltran BE, de Boer JP, Chakhachiro Z, Ye D, Clark D, Young KH, Medeiros LJ. Breast implant-associated anaplastic large-cell lymphoma: long-term follow-up of 60 patients. J Clin Oncol. 2014, 32(2):114-1120.
  • Arribas AJ, Rinaldi A, Mensah AA, Kwee I, Cascione L, Robles EF, Martinez-Climent JA, Oscier D, Arcaini L, Baldini L, Marasca R, Thieblemont C, Briere J, Forconi F, Zamò A, Bonifacio M, Mollejo M, Facchetti F, Dirnhofer S, Ponzoni M, Bhagat G, Piris MA, Gaidano G, Zucca E, Rossi D, Bertoni F. DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features. Blood. 2015, 125(12):1922-1931.
  • Montanari F, Radeski D, Seshan V, Alobeid B, Bhagat G, O'Connor OA. Recursive partitioning analysis of prognostic factors in post-transplant lymphoproliferative disorders (PTLD): a 120 case single institution series. Br J Haematol. 2015, 171(4):491-500.
  • Margolskee E, Jobanputra V, Jain P, Chen J, Ganapathi K, Nahum O, Levy B, Morscio J, Murty V, Tousseyn T, Alobeid B, Mansukhani M, Bhagat G. Genetic landscape of T- and NK-cell post-transplant lymphoproliferative disorders. Oncotarget. 2016, 7(25):37636-37648.
  • Ganapathi KA, Jobanputra V, Iwamoto F, Jain P, Chen J, Cascione L, Nahum O, Levy B, Xie Y, Khattar P, Hoehn D, Bertoni F, Murty VV, Pittaluga S, Jaffe ES, Alobeid B, Mansukhani MM, Bhagat G. The genetic landscape of dural marginal zone lymphomas. Oncotarget. 2016, 7(28):43052-43061.
  • Castellanos-Rubio A, Fernandez-Jimenez N, Kratchmarov R, Luo X, Bhagat G, Green PH, Schneider R, Kiledjian M, Bilbao JR, Ghosh S. A long noncoding RNA associated with susceptibility to celiac disease. Science. 2016, 352(6281):91-95.
  • De Silva NS, Anderson MM, Carette A, Silva K, Heise N, Bhagat G, Klein U. Transcription factors of the alternative NF-κB pathway are required for germinal center B-cell development. Proc Natl Acad Sci U S A. 2016, 113(32):9063-9068.
  • Xia Y, Xu-Monette ZY, Tzankov A, Li X, Manyam GC, Murty V, Bhagat G, Zhang S, Pasqualucci L, Visco C, Dybkaer K, Chiu A, Orazi A, Zu Y, Richards KL, Hsi ED, Choi WW, van Krieken JH, Huh J, Ponzoni M, Ferreri AJ, Møller MB, Parsons BM, Winter JN, Piris MA, Westin J, Fowler N, Miranda RN, Ok CY, Li Y, Li J, Medeiros LJ, Young KH. Loss of PRDM1/BLIMP-1 function contributes to poor prognosis of activated B-cell-like diffuse large B-cell lymphoma. Leukemia. 2017, 31(3):625-636.
  • Matnani R, Ganapathi KA, Lewis SK, Green PH, Alobeid B, Bhagat G. Indolent T- and NK-cell lymphoproliferative disorders of the gastrointestinal tract: a review and update.Hematol Oncol. 2017, 35(1):3-16.

For a complete list of publications, please visit PubMed.gov