Ira A. Tabas, MD, PhD

Board Certifications: 
Endocrinology, Internal Medicine

Overview

Areas of Expertise / Conditions Treated

Molecular Medicine

Academic Appointments

  • Richard J. Stock Professor of Medicine (Immunology)
  • Professor of Pathology & Cell Biology at CUMC

Administrative Titles

  • Vice-Chair of Research, Department of Medicine

Dr. Tabas received his medical degree and his doctorate in biochemistry from Washington University in St. Louis, Missouri. He then completed an internship and residency in internal medicine and a fellowship in endocrinology and metabolism at Columbia University Medical Center in New York City. During that period, Dr. Tabas also conducted a postdoctoral fellowship in the laboratory of Dr. Alan Tall in the Department of Medicine at Columbia University. He joined the Columbia faculty in 1985 and is currently the Richard J. Stock Professor and Vice-Chair of Research in the Department of Medicine and Professor of Pathology and Cell Biology (in Physiology and Cellular Biophysics).

Dr. Tabas' honor include the American Heart Association Established Investigator Award, the Columbia University Doctor Harold and Golden Lamport Research Award, the American Heart Association/ATVB Council Special Recognition Award, the Richard J. Stock Professorship in the Department of Medicine of Columbia University, and the 2011 Alumni Achievement Award from Washington University School of Medicine. He was elected to both the Society for Clinical Investigation and the Association of American Physicians.

Email: iat1@cumc.columbia.edu

Hospital Affiliations

  • NewYork-Presbyterian/Columbia

Gender

  • Male

Insurance Accepted

Aetna

  • EPO
  • HMO
  • Medicare Managed Care
  • NY Signature
  • POS
  • PPO
  • Signature Administrators
  • Student Health

Cigna

  • EPO
  • Great West
  • HMO
  • POS
  • PPO

Emblem/GHI

  • HMO
  • Medicare Managed Care
  • PPO

Emblem/HIP

  • ConnectiCare
  • EPO
  • Essential Plan
  • HMO
  • Medicaid Managed Care
  • Medicare Managed Care
  • POS
  • PPO
  • Select Care (Exchange)
  • Vytra

Empire Blue Cross Blue Shield

  • Blue Priority
  • EPO
  • HMO
  • Medicare (Mediblue)
  • NYP Employee Plan
  • Pathway (Exchange)
  • POS
  • PPO

Local 1199

  • Local 1199

MagnaCare

  • MagnaCare

Multiplan

  • Multiplan

Oxford Health Plans

  • Freedom
  • Liberty
  • Medicare Managed Care

UnitedHealthcare

  • Columbia University Employee Plan
  • Compass (Exchange)
  • EPO
  • Essential Plan
  • HMO
  • Medicaid (Community Plan)
  • Medicare Managed Care
  • POS
  • PPO

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Credentials & Experience

Education & Training

  • Washington University School of Medicine, St. Louis, MO
  • Internship: Columbia Presbyterian Medical Center, NY
  • Residency: Columbia Presbyterian Medical Center, NY
  • Fellowship: Columbia Presbyterian Medical Center, NY

Board Certifications

  • Endocrinology
  • Internal Medicine

Research

Dr. Tabas' research focuses on the molecular-cellular mechanisms of atherosclerosis, with an emphasis on macrophage cell biology, endoplasmic reticulum-induced cell death (apoptosis), mechanisms involved in the generation of clinically dangerous atherosclerotic plaques, translational work in mouse models of atherosclerosis, and mechanistic-based correlative studies on human disease tissue. His recent activities have expanded into mechanisms of atherosclerosis in diabetes and obesity, including new studies on liver and adipose tissue. He has lectured worldwide and published approximately 175 original research articles and reviews. These papers have been published in Cell, Nature, Nature Cell Biology, Nature Reviews Immunology, Cell Metabolism, Journal of Clinical Investigation, Proceedings of the National Academy of Science USA, Journal of Cell Biology, and Journal of Biological Chemistry. He has served on the editorial board of the Journal of Biological Chemistry, was Deputy Editor of the Journal of Clinical Investigation from 2002-2007, and is currently on the Board of Reviewing Editors for Science.

Research Interests

  • Cellular and molecular processes related to arterial wall biology and atherogenesis

Grants

MECHANISMS OF ATHEROGENESIS IN INSULIN RESISTANCE (Federal Gov)

Aug 1 2018 - Jun 30 2023

TAZ AND YAP IN NON-ALCOHOLIC STEATOHEPATITIS AND ITS COMPLICATIONS (Federal Gov)

Jan 1 2018 - Dec 31 2021

CAMKII/MK2 SIGNALING IN CARDIOMETABOLIC DISEASE (Federal Gov)

Dec 15 2017 - Nov 30 2021

MACROPHAGE-LIPOPROTEIN INTERACTIONS (Federal Gov)

Jul 15 2017 - Apr 30 2021

SIRNA TARGETING HEPATOCYTE TAZ AS A NOVEL TREATMENT FOR NON-ALCOHOLIC STEATOHEPATITIS (Private)

Jul 12 2018 - Jul 11 2020

MERTK CLEAVAGE AND SIGNALING IN ATHEROSCLEROSIS (Federal Gov)

Mar 15 2016 - Feb 29 2020

ENHANCING INFLAMMATION RESOLUTION IN ATHEROSCLEROSIS VIA TARGETED NANOPARTICLE-MEDIATED DELIVERY OF BIOLOGICS (Federal Gov)

Jan 1 2016 - Dec 31 2019

MECHANISMS AND CONSEQUENCES OF STRESS-INDUCED MACROPHAGE DEATH IN ATHEROSCLEROSIS (Federal Gov)

Mar 1 2013 - Feb 28 2019

CAMKII IN ADVANCED ATHEROSCLEROSIS AND INSULIN RESISTANCE (Private)

Jul 1 2017 - Jun 30 2018

TARGETING HEPATOCYTE TAZ TO TREAT NON-ALCOHOLIC STEATOHEPATITIS (Private)

Dec 20 2016 - Dec 19 2017

A NEW HEPATIC DPP4 PATHWAY THAT PROMOTES VISCERAL FAT INFLAMMATION (Private)

Jul 1 2015 - Jun 30 2017

THE ROLE OF MERTK CLEVAGE IN ADVANCE ATHEROSCLEROSIS (Private)

Jul 1 2015 - Jun 30 2017

TARGETING OF A NOVEL MODULE IN GLUCAGON SIGNALING AS A THERAPEUTIC STRATEGY FOR TYPE 2 (Private)

Jan 1 2015 - Mar 31 2017

MECHANISMS OF DEFECTIVE EFFEROCYTOSIS IN ATHEROSCLEREOSIS (Federal Gov)

Dec 1 2011 - Nov 30 2015

AUTOPHAGY IN ADVANCED ATHEROSCLEROSIS (Federal Gov)

Jan 1 2011 - Nov 30 2015

A NANOTHERAPEUTIC APPROACH TO DEFECTIVE INFLAMMATION RESOLUTION IN ATHEROSCLEROSIS. (Federal Gov)

Aug 13 2010 - Aug 12 2015

SPECIALIZED PRO-RESOLVING MEDIATORS IN ATHEROSCLEROSIS (Federal Gov)

Aug 1 2013 - Jul 31 2015

ROLE OF CAMKLL IN ATHEROSCLEROSIS AND PROATHEROGENIC EFFECTS RELATED TO INSULIN RESISTANCE (Private)

Jan 1 2011 - Dec 31 2014

A NOVEL MOLECULAR MECHANISM LINKING PROLONGED ER STRESS WITH THE MITOCHODRIAL PATHWAY OF APOPTOSIS (Private)

Jul 1 2011 - Jun 30 2013

EFFEROCYTOSIS IN CVD & INFLAMMATION (Private)

Jul 1 2009 - Jun 30 2013

ROLE OF INNATE IMMUNITY IN STRESS-INDUCED APOPTOSIS AND PLAQ UE PROGRESSION IN ATHEROSCLEROSIS (Private)

Jan 1 2010 - Dec 31 2011

ROLE OF INNATE IMMUNITY IN STRESS-INDUCED APOPTOSIS AND PLAQ UE PROGRESSION IN ATHEROSCLEROSIS (Private)

Jul 1 2009 - Jun 30 2011

RESEARCH COLLABORATION AGREEMENT (NMA) W/ GALAXOSMITHKLINE(G SK); UNIVERSITY OF PENNSYLVANIA(PENN) (Private)

Mar 1 2010 - Feb 28 2011

INTERACTION OF ATHEROGENIC LIPOPROTEINS WITH MACROPHAGES (Federal Gov)

Mar 15 1997 - Feb 28 2011

THE ROLE OF PLANT STEROLS IN ATHEROSCLEROTIC PLAQUE STABILIT Y AND MORPHOLOGY (Private)

Dec 18 2008 - Dec 17 2010