Darrell J. Yamashiro, MD, PhD

Expertise in: 
Cancer Care
Board Certifications: 
Pediatric Hematology-Oncology, Pediatrics
Accepting New Patients
Treats Children
Profile Headshot

Overview

Areas of Expertise / Conditions Treated

Cancer Care, Pediatric Liver Cancer, Hepatoblastoma, Angiogenesis, Wilm's Tumor, Pediatric Solid Tumors, Neuroblastoma

Academic Appointments

  • Associate Professor of Pathology & Cell Biology at CUMC
  • Associate Professor of Pediatrics at CUMC

Administrative Titles

  • Director, Hematology/Oncology/SCT Fellowship Program

Pediatric Oncology - NewYork-Presbyterian/Morgan Stanley Children's Hospital

Darrell J. Yamashiro, MD, PhD is a pediatric oncologist who specializes in the care of children with pediatric solid tumors, especially neuroblastoma, Wilms' tumor and other kidney tumors, and liver tumors such hepatoblastoma and hepatocellular carcinoma.

Although liver tumors in children are rare (they account for only one to two percent of childhood cancers), they can be very complex and require a multidisciplinary approach for optimal management. Dr. Yamashiro enjoys working as part of a team of physicians, nurse practitioners, nurses, social workers, child life specialists, and other dedicated healthcare professionals who deeply care about patients and who provide care with compassion and comfort.

Dr. Yamashiro also conducts basic science research. The latest advances in tumor genetics and the design of innovative therapies make this a very exciting time. For example, he and his team have done extensive research on the genetics of hepatoblastoma and developed mouse models, entering the phase of research where they are taking a personalized/precision medicine approach to this disease. They are also identifying novel genes that specifically target neuroblastoma-information that may be used to create targeted therapies.

Email: dy39@cumc.columbia.edu

Hospital Affiliations

  • NewYork-Presbyterian/Morgan Stanley Children's Hospital
  • NewYork-Presbyterian/Columbia

Gender

  • Male

Insurance Accepted

Aetna

  • EPO
  • HMO
  • Medicare Managed Care
  • NY Signature
  • POS
  • PPO
  • Signature Administrators
  • Student Health

Affinity

  • Essential Plan
  • Medicaid Managed Care
  • Medicare Managed Care

Amida Care

  • Special Needs Plan

Cigna

  • EPO
  • Great West
  • HMO
  • POS
  • PPO

Emblem/GHI

  • HMO
  • Medicare Managed Care
  • PPO

Emblem/HIP

  • ConnectiCare
  • EPO
  • Essential Plan
  • HMO
  • Medicaid Managed Care
  • Medicare Managed Care
  • POS
  • PPO
  • Select Care (Exchange)
  • Vytra

Empire Blue Cross Blue Shield

  • Blue Priority
  • EPO
  • HMO
  • Medicare (Mediblue)
  • NYP Employee Plan
  • Pathway (Exchange)
  • POS
  • PPO

Empire Blue Cross Blue Shield HealthPlus

  • Child/Family Health Plus
  • Essential Plan
  • Medicaid Managed Care

Fidelis Care

  • Child/Family Health Plus
  • Medicaid Managed Care
  • Medicare Managed Care

Healthfirst

  • Child/Family Health Plus
  • Medicaid Managed Care
  • Medicare Managed Care

Local 1199

  • Local 1199

MagnaCare

  • MagnaCare

Multiplan

  • Multiplan

Oxford Health Plans

  • Freedom
  • Liberty
  • Medicare Managed Care

POMCO

  • POMCO

UnitedHealthcare

  • Columbia University Employee Plan
  • Compass (Exchange)
  • EPO
  • Essential Plan
  • HMO
  • Medicaid (Community Plan)
  • Medicare Managed Care
  • POS
  • PPO

VNSNY CHOICE

  • Medicare Managed Care
  • SelectHealth

WellCare

  • Medicaid Managed Care
  • Medicare Managed Care

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Credentials & Experience

Education & Training

  • New York University School of Medicine
  • Internship: Children's Hospital of Philadelphia
  • Residency: Children's Hospital of Philadelphia
  • Fellowship: Children's Hospital of Philadelphia

Board Certifications

  • Pediatric Hematology-Oncology
  • Pediatrics
NY Top Doctor

Research

Grants

SOHN COLLABORATIVE FOR PEDIATRIC CANCER RESEARCH (Private)

Apr 22 2014 - Dec 31 2016

SOHN COLLABORATIVE FOR PEDIATRIC CANCER RESEARCH (Private)

Apr 22 2014 - Apr 21 2016

PEDIATRIC ONCOLOGY STUDENT TRAINING (POST) PROGRAM (Private)

Apr 1 2015 - Mar 31 2016

IDENTIFICATION OF TFAP4 (TRANSCRIPTION FACTOR AP-4/ACTIVATING ENHANCER BINDING PROTEIN) AS A POTENTIAL MASTER REGULATOR/SYNTHETIC LETHAL GENE OF MYCN AMPLIFIED NEUROBLASTOMA (Private)

Jul 1 2013 - Jul 1 2015

VEGF BLOCKADE AND ALTERNATIVE ANGIOGENIC PATHWAYS IN NEUROBLASTOMA (Federal Gov)

Apr 10 2008 - Jan 31 2014

USING CONTRAST ENHANCED ULTRASOUND TO ASSESS THE EFFICACY OF ADT INHIBITION AS A RADIOSENSITIZER IN EXPERIMENTAL NEUROBLASTOMA (Private)

May 1 2013 - Aug 31 2013

NOVEL MICROBUBBLE-BASED GENE DELIVERY VEHICLES TARGETING SOL ID TUMORS (Private)

Jul 1 2009 - Jan 31 2011

THE ROLE OF NOTCH SIGNALING IN NEUROBLASTOMA ANGIOGENESIS (Private)

Jul 1 2007 - Jun 30 2010

Selected Publications

Banerjee D, Hernandez SL, Garcia A, Kangsamaksin T, Sbiroli E, Andrews J, Forrester LA, Wei N, Kadenhe-Chiweshe A, Shawber CJ, Kitajewski JK, **Kandel JJ, **Yamashiro DJ. Notch suppresses angiogenesis and progression of hepatic metastases. Cancer Res. 2015;75(8):1592-1602. PMID: 25744722; PMCID: PMCPMC4401639.

Glade Bender J, Blaney SM, Borinstein S, Reid JM, Baruchel S, Ahern C, Ingle AM, Yamashiro DJ, Chen A, Weigel B, Adamson PC, Park JR. A phase I trial and pharmacokinetic study of aflibercept (VEGF Trap) in children with refractory solid tumors: a children's oncology group phase I consortium report. Clin Cancer Res. 2012;18(18):5081-5089. PMID: 22791883; PMCID: PMC3445751.

Glade Bender JL, Adamson PC, Reid JM, Xu L, Baruchel S, Shaked Y, Kerbel RS, Cooney-Qualter EM, Stempak D, Chen HX, Nelson MD, Krailo MD, Ingle AM, Blaney SM, Kandel JJ, Yamashiro DJ, Children's Oncology Group S. Phase I trial and pharmacokinetic study of bevacizumab in pediatric patients with refractory solid tumors: a Children's Oncology Group Study. J Clin Oncol. 2008;26(3):399-405. PMID: 18202416.