Anthony N. Sireci, MD

Expertise in: 
Clinical Genetics and Genomics (MD)
Board Certifications: 
Clinical Pathology
Accepting New Patients
Profile Headshot

Overview

Areas of Expertise / Conditions Treated

Clinical Genetics and Genomics (MD), Clinical Chemistry, Laboratory Medicine, Cytogenetic Study, Genetic Testing, Genetic Disorders, Genetic Screening

Academic Appointments

  • Assistant Professor of Pathology & Cell Biology at CUMC

Administrative Titles

  • Physician Manager and Assistant Director, Laboratory of Personalized Genomic Medicine
  • Assistant Director, Biochemical Genetics

Hospital Affiliations

  • NewYork-Presbyterian/Columbia

Gender

  • Male

Credentials & Experience

Education & Training

  • Johns Hopkins University School of Medicine
  • Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center

Board Certifications

  • Clinical Pathology

Research

Selected Publications

  1. Oberg, J.; Glade Bender, J.; Sulis, ML.; Pendrick, D.; Sireci, A.; Hsiao,S.; Turk, A.; Dela Cruz, F.; Hibshoosh,H.; Remotti,H.; Zybler, R.; Pang, J.; Diolaiti, D.; Koval, C.; Andrews, S.; Garvin, J.; Yamashiro, D.; Chung, W.; Emerson, S.; Nagy, P.; Mansukhani, M.; Kung, A. Implementation of Next Generation Sequencing into Pediatric hematology-Oncology Practice: moving beyond actionable alterations. Genome Med.
  2. Sireci, A., Aggarwal, V., Turk, A., Gindin, T., Mansukahni, M., Hsiao, S. Clinical Genomic Profiling of a Diverse Array of Oncology Specimens at a Large Academic Medical Center: identification of targetable variants and experience with reimbursement. J Mol Diag.
  3. Margolskee, E.; Bao, F.; de Gonzalez, AK.; Moreira, RK., Lagana, S.; Sireci, AN., Sepulveda, AR.; Remotti, H.; Lefkowitch, JH., Salomao, M. Hepatocellular adenoma classification: a comparative evaluation of immunohistochemistry and targeted mutational analysis. Diagn Pathol. (2016) March 9;11(1):27
  4. Qiu, W.;  Tang, SM.; Lee, S.; Turk, AT.; Sireci, AN.; Qui, A., et. al.  Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice with Activated KRAS. Gastroenterology. (2016) Jan; 150 (1): 218-228
  5. Pham, H; Sireci, A.; Kim, C; Schwartz, J. Cost-effectiveness Analysis of Plasma vs. Recombinant Factor VIIa for Placing Intracranial Pressure Monitors in Pre-transplant Patients with Acute Liver Failure. Clinical and Applied Thrombosis and Hemostasis. (2014) March; 20(6); 607-614
  6. Allen, A; Sireci, A; Colovai, A; Baghat, G; Alobeid, B. Early T-cell precursor leukemia/lymphoma in adults and children. Leukemia Research. (2013) September; 37(9):1027-34
  7. Callan, E.; Hod, E.; Sireci, A.; Spitalnik, S.; Transfusion of 28 Day-Old Leukoreduced or Non-Leukoreduced Stored Red Blood Cells Induces an Inflammatory Response in Healthy Dogs. Vox Sang. (2013). Nov; 105(4); 319-27
  8. McMillen, B; Bautista, J; Sireci, A,N; Stotler, B; Kratz,A. Low Accuracy of Manual White Blood Cell Count in Amniotic Fluid. J Obst and Gyn (2012). May;33(4):364-6

  9. Narayan, S; Master, S.R; Sireci, AN; Bierl, C; Stanely, P; Li, C; Stanely, CA; Bennett, MJ Short-Chain 3-Hydroxyacyl-Coenzyme A Dehydrogenase Associates with a Protein Super-Complex Integrating Multiple Metabolic Pathways. PLoS (2012) Apr 9;7(4).

  10. Hod EA, Brittenham GM, Billote GB, Francis RO, Ginzburg YZ, Hendrickson JE, Jhang J, Schwartz J, Sharma S, Sheth S, Sireci AN, Stephens HL, Stotler BA, Wojczyk BS, Zimring JC, Spitalnik SL. Transfusion of human volunteers with older, stored red blood cells produces extravascular hemolysis and circulating non-transferrin-bound iron. Blood. (2011) Dec 15;118(25):6675-82

  11.  Hussein S, Gill KZ, Sireci AN, Colovai AI, Small T, Emmons FN, Murty VV, Bhagat G, Alobeid B. Aberrant T-cell antigen expression in B lymphoblastic leukaemia. Br J Haematol. ( 2011);155(4):449-56.

  12. Sireci, A; Herlitz, L; Lee, K; Bautista, J; Kratz, A. Validation and Implementation of an Algorithm for Reporting the Automated Absolute Neutrophil Count From Selected Flagged Specimens. AJCP (2010); 134: 720-5.
  13. Sireci, A; Schlaberg, R; Kratz, A. A Method for Optimizing and Validating Instrument- Specific Flagging Criteria. Arch Pathol and Lab Med (2010); 134; 1528-33.
  14. Sireci, A; Crapanzano, J; Mansukhani, M; Wright, T; Babioc, A; Saqi, A.  Atypical Glandular Cells (AGC): ThinPrep Imaging System (TIS), Manual Screening (MS) and Correlation with Hybrid Capture 2 (HC2) HPV DNA Testing. Diag Cytopathol.(2010); 38:705-709.